Dual-Level Interaction Aware Heterogeneous Graph Neural Network for Medicine Package Recommendation

Research on Medical Package Recommendation Systems: Heterogeneous Graph Neural Network Based on Dual-Level Interaction Awareness With the widespread application of electronic health records (EHRs) in the medical field, how to mine potential and valuable medical knowledge to support clinical decision-making has become an important research direction...

An Explainable and Personalized Cognitive Reasoning Model Based on Knowledge Graph: Toward Decision Making for General Practice

An Explainable and Personalized Cognitive Reasoning Model Based on Knowledge Graph: Toward Decision Making for General Practice

An Explainable and Personalized Cognitive Reasoning Model Based on Knowledge Graph: Toward Decision Making for General Practice Background General medicine, as an important part of community and family healthcare, covers different ages, genders, organ systems, and various diseases. Its core concept is human-centered, family-based, emphasizing long-...

Knowledge-Enhanced Graph Topic Transformer for Explainable Biomedical Text Summarization

Application of Knowledge-Enhanced Graph Topic Transformer in Interpretable Biomedical Text Summarization Research Background Due to the continuous increase in the volume of biomedical literature, the task of automatic biomedical text summarization has become increasingly important. In 2021 alone, 1,767,637 articles were published in the PubMed data...

Graph Neural Networks with Multiple Prior Knowledge for Multi-omics Data Analysis

Graph Neural Networks with Multiple Prior Knowledge for Multi-omics Data Analysis

Multiple Prior Knowledge Graph Neural Network in Multi-Omics Data Analysis Background Introduction Precision medicine is an important field for the future of healthcare as it provides personalized treatment plans for patients, improving treatment outcomes and reducing costs. For instance, due to the complex clinical, pathological, and molecular cha...

Stage-Aware Hierarchical Attentive Relational Network for Diagnosis Prediction

Application of Hierarchical Attentive Relational Network in Diagnostic Prediction In recent years, Electronic Health Records (EHR) have become extremely valuable in improving medical decision-making, online disease detection, and monitoring. At the same time, deep learning methods have also achieved great success in utilizing EHR for health risk pr...

Graph-based Conditional Generative Adversarial Networks for Major Depressive Disorder Diagnosis with Synthetic Functional Brain Network Generation

Graph-based Conditional Generative Adversarial Networks for Major Depressive Disorder Diagnosis with Synthetic Functional Brain Network Generation

Graph-Based Conditional Generative Adversarial Network for Generating Synthetic Functional Brain Networks to Diagnose Major Depressive Disorder Research Background: Major Depressive Disorder (MDD) is a widespread mental disorder that affects millions of people’s lives and poses a significant threat to global health. Studies have shown that function...

Epilepsy Surgery for Dominant-Side Mesial Temporal Lobe Epilepsy without Hippocampal Sclerosis

Evaluation of Efficacy of Epilepsy Surgery for Dominant Mesial Temporal Lobe Epilepsy without Hippocampal Sclerosis Original Research | Journal of Clinical Neuroscience 111 (2023) 16-21 Introduction Approximately 0.5%-1% of the global population suffers from epilepsy (Fiest et al. 2017), with about 30% of these patients being refractory to medicati...

Decreased Thalamocortical Connectivity in Resolved Rolandic Epilepsy

Decreased Thalamocortical Connectivity in Resolved Rolandic Epilepsy

Thalamocortical Connectivity Reduction in Rolandic Epilepsy Rolandic Epilepsy (RE), also known as self-limited epilepsy with centrotemporal spikes (SELECTS), is the most common localized developmental epileptic encephalopathy. This type of epilepsy is typically accompanied by transient mild to severe cognitive symptoms, sleep-related rolandic spike...

Functional Connectivity Changes in Mild Cognitive Impairment: A Meta-Analysis of M/EEG Studies

Changes in Functional Connectivity in Mild Cognitive Impairment: A Meta-Analysis of M/EEG Studies Background and Objectives Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by memory loss and cognitive impairment. AD is the leading cause of cognitive disorders in the elderly, accounting for approximately 60% to 80% of global c...

Pupillometry Reveals Resting State Alpha Power Correlates with Individual Differences in Adult Auditory Language Comprehension

Study on the Correlation between Adult Auditory Language Comprehension and Resting-State Alpha Wave Power Academic Background and Research Question Although individual differences in adult language processing have been documented in literature, the neural basis largely remains to be explored. Existing research primarily focuses on how general cogni...