Development and Validation of a Deep Learning Radiomics Model with Clinical-Radiological Characteristics for the Identification of Occult Peritoneal Metastases in Patients with Pancreatic Ductal Adenocarcinoma

Development and Validation of a Deep Learning Radiomics Model Combined with Clinical Radiological Features for Predicting Occult Peritoneal Metastasis in Patients with Pancreatic Ductal Adenocarcinoma Background Pancreatic ductal adenocarcinoma (PDAC) is an extremely lethal malignancy with a 5-year survival rate of approximately 11%. The poor progn...

Laser Interstitial Thermal Therapy in Neurosurgery: A Single-Surgeon Experience of 313 Patients

Laser Interstitial Thermal Therapy in Neurosurgery: A Single-Surgeon Experience of 313 Patients

Clinical Study Report on Laser Interstitial Thermal Therapy (LITT) in Neurosurgery Background Introduction With the continuous progress of modern medical technology, Laser Interstitial Thermal Therapy (LITT) has gradually gained a foothold in the field of neurosurgical tumor treatment, especially in treating intracranial lesions that are difficult ...

Deep Learning Combining Mammography and Ultrasound Images to Predict the Malignancy of BI-RADS US 4a Lesions in Women with Dense Breasts: A Diagnostic Study

Research on Using Deep Learning to Combine Mammography and Ultrasound Images for Predicting Malignancy of BI-RADS US 4A Lesions in Women with Dense Breasts Background Breast cancer is the most common malignant tumor in women, with a relatively high incidence and mortality rate. Previous studies have found that women with dense breasts are more like...

Precise and safe pulmonary segmentectomy enabled by visualizing cancer margins with dual-channel near-infrared fluorescence

Precise and Safe Lung Segmentectomy Enabled by Dual-Channel Near-Infrared Fluorescence Tumor and Pleural Demarcation Lung cancer is a leading cause of cancer-related deaths globally. Since the introduction of computed tomography screening, the early detection rate of lung cancer has greatly increased, significantly reducing mortality rates. Studies...

Turning the Operating Room into a Mixed-Reality Environment: A Prospective Clinical Investigation for Cerebral Aneurysm Clipping

Turning the Operating Room into a Mixed-Reality Environment: A Prospective Clinical Investigation for Cerebral Aneurysm Clipping

Transforming the Operating Room into a Mixed Reality Environment: A Prospective Clinical Study on Aneurysm Clipping The surgical treatment of cerebral aneurysms is a highly complex and delicate process in neurosurgery. Researchers continue to explore new technologies and methods to improve surgical outcomes. In recent years, the development of Mixe...

SIRT1-RAB7 Axis Attenuates NLRP3 and STING Activation through Late Endosomal-Dependent Mitophagy during Sepsis-Induced Acute Lung Injury

The SIRT1-Rab7 Axis Regulates NLRP3 and STING Activation in Sepsis-Induced Acute Lung Injury via Terminal Endosome-Dependent Mitophagy Academic Background Acute lung injury (ALI) is one of the leading causes of death in septic patients, primarily due to the pro-inflammatory changes and permeability defects in endothelial cells (ECs). Mitochondrial ...

A Novel Stratification Scheme Combined with Internal Arteries in CT Imaging for Guiding Postoperative Adjuvant Transarterial Chemoembolization in Hepatocellular Carcinoma: A Retrospective Cohort Study

Retrospective Cohort Study on Innovative Stratification Scheme Based on Postoperative Combined CT Imaging to Guide Postoperative Adjuvant Transarterial Chemoembolization for Hepatocellular Carcinoma Background Hepatocellular carcinoma (HCC) is the sixth most common cancer globally and the fourth leading cause of cancer-related deaths. For HCC, live...

Watch-and-Wait Strategy vs. Resection in Patients with Radiologic Complete Response After Conversion Therapy for Initially Unresectable Hepatocellular Carcinoma: A Propensity Score-Matching Comparative Study

Observation vs Surgical Resection for Initial Unresectable Hepatocellular Carcinoma after Conversion Therapy Background Hepatocellular carcinoma (HCC) is the sixth most common cancer globally and the third leading cause of cancer-related mortality. Partial hepatectomy can provide a 5-year survival rate of 70-80% in the treatment of early-stage HCC....

Distribution of Coronal Plane Alignment of the Knee Classification in Chinese Osteoarthritic and Healthy Population: A Retrospective Cross-sectional Observational Study

A Retrospective Cross-Sectional Observational Study on the Distribution of Coronal Plane Alignment Classifications in Chinese Osteoarthritic and Healthy Populations Research Background Neutral mechanical alignment (MA) of the knee is considered the cornerstone of successful and durable total knee arthroplasty (TKA). However, the existence of “const...

Artificial Intelligence-Based Classification of Breast Lesion from Contrast Enhanced Mammography: A Multicenter Study

Multi-center Study on Artificial Intelligence-based Classification of Breast Lesions In the field of breast cancer, early diagnosis is crucial for improving treatment efficacy and survival rate. Breast cancer can be mainly divided into two categories: in situ carcinoma and invasive carcinoma, which have significant differences in treatment strategi...