Semi-Supervised Thyroid Nodule Detection in Ultrasound Videos

Semi-Supervised Thyroid Nodule Detection in Ultrasound Videos

Research Report on Semi-Supervised Detection of Thyroid Nodules in Ultrasound Videos Research Background Thyroid nodules are common thyroid diseases. Early screening and diagnosis of thyroid nodules typically rely on ultrasound examinations, a common non-invasive detection method used for detecting various diseases such as thyroid nodules, breast c...

Study on the Safety and Efficacy of Algorithmically Controlled Electroporation for Treating Spontaneous Equine Melanoma

Study on the Safety and Efficacy of Algorithmically Controlled Electroporation for Treating Spontaneous Equine Melanomas In recent years, electroporation, specifically irreversible electroporation (IRE), has shown significant potential as a non-thermal ablation technique in tumor treatment. Compared to traditional thermal ablation methods, IRE can ...

Antibody-Displaying Extracellular Vesicles for Targeted Cancer Therapy

Antibody-Displaying Extracellular Vesicles for Targeted Cancer Therapy

The Application of Antibodies Displaying Extracellular Vesicles in Targeted Cancer Therapy Extracellular Vesicles (EVs) have been extensively researched as natural delivery carriers and mediators of biological signals in various tissues. In this study, researchers utilized these characteristics of EVs to demonstrate a modular delivery system for ca...

Precision Colorectal Cancer Screening with Fecal Hemoglobin Concentration-Guided Intervals

Precise Colorectal Cancer Screening Based on Customized Intervals Using Fecal Hemoglobin Concentration Researchers: Amy Ming-Fang Yen, Yang-Ching Chen, Yu-Lin Ding, Wen-Zhu Qiu, Han-Mo Qiu, Tony Hsiu-Hsi Chen, Sam Li-Sheng Chen Academic Background Colorectal cancer (CRC) is the third most prevalent malignancy worldwide. In recent years, significant...

Oncolytic Mineralized Bacteria as Potent Locally Administered Immunotherapeutics

Oncolytic Mineralized Bacteria May Be Used for Tumor Immunotherapy via Local Injection Research Background As a novel cancer treatment method, bacteria-based cancer immunotherapy has a long history dating back to the late 19th century when heated, inactivated bacteria were used to treat sarcomas. Initial trials found that these bacteria could trigg...

Generation of Synthetic Whole-Slide Image Tiles of Tumours from RNA-Sequencing Data via Cascaded Diffusion Models

Generation of Synthetic Whole-Slide Image Tiles of Tumours from RNA-Sequencing Data via Cascaded Diffusion Models

Generation of Synthetic Whole-Slide Images of Tumors from RNA Sequencing Data via Cascaded Diffusion Models A recent study published in Nature Biomedical Engineering, titled “Generation of Synthetic Whole-Slide Image Tiles of Tumours from RNA-Sequencing Data via Cascaded Diffusion Models,” has garnered significant attention. This research, conducte...

Prediction of tumor origin in cancers of unknown primary origin with cytology-based deep learning

Prediction of tumor origin in cancers of unknown primary origin with cytology-based deep learning

Background Introduction Cancer of Unknown Primary (CUP) is a type of malignant disease that is confirmed to be metastatic through histopathology but whose primary site cannot be identified using conventional baseline diagnostic methods. CUP presents significant diagnostic and therapeutic challenges in clinical practice and is believed to account fo...

Intrathecal Bivalent CAR T Cells Targeting EGFR and IL13Rα2 in Recurrent Glioblastoma: Phase 1 Trial Interim Results

Intrathecal Bivalent CAR T Cells Targeting EGFR and IL13Rα2 in Recurrent Glioblastoma: Phase 1 Trial Interim Results

The Effectiveness of Bivalent CAR T-Cell Therapy Targeting EGFR and IL13Rα2 in Treating Recurrent Glioblastoma In recent years, the treatment of recurrent glioblastoma (RGBM) has been continually explored and improved, yet overall survival rates remain less than one year, presenting a significant challenge. The limitations of existing treatments an...

Integrative Molecular and Spatial Analysis Reveals Evolutionary Dynamics and Tumor-Immune Interplay of In Situ and Invasive Acral Melanoma

Integrative Molecular and Spatial Analysis Reveals Evolutionary Dynamics and Tumor-Immune Interplay of In Situ and Invasive Acral Melanoma

Integrated Molecular and Spatial Analysis Reveals Evolutionary Dynamics and Tumor-Immune Interactions in In Situ and Invasive Acral Melanoma Academic Background of the Paper Melanoma is a type of skin cancer, and acral melanoma (AM) is a kind that occurs on non-exposed areas such as the palms, soles, and under the nails and is particularly common a...

Development and Standardization of an Osteoradionecrosis Classification System in Head and Neck Cancer: Implementation of a Risk-Based Model

Development and Standardization of an Osteoradionecrosis Classification System in Head and Neck Cancer: Implementation Based on Risk Model In recent years, the side effects brought by the treatment of head and neck cancer (HNC), especially radiotherapy, have become a focal point of academic attention. Osteoradionecrosis (ORN) is one of the most sev...