Identifying New Classes of Financial Price Jumps with Wavelets

Research Report on Identifying New Classes of Financial Price Jumps Using Wavelets Academic Background Price jumps in financial markets refer to significant price fluctuations occurring within an extremely short period, typically caused by exogenous factors (such as sudden news) or endogenous factors (internal market feedback mechanisms). Distingui...

Biochemical and Structural Bases for Talin ABSS–F-Actin Interactions

Academic Background In cell biology, focal adhesions (FAs) are key connection points between cells and the extracellular matrix (ECM), linking integrin receptors to the intracellular actin cytoskeleton. They play a crucial role in cell migration and polarization. Talin is a core protein in focal adhesions that directly connects integrin receptors t...

Out-of-Distribution Generalization via Composition: A Lens Through Induction Heads in Transformers

Study on Out-of-Distribution Generalization and Composition Mechanisms in Large Language Models Paper Background In recent years, large language models (LLMs) such as GPT-4 have demonstrated remarkable creativity in handling novel tasks, often solving problems with just a few examples. These tasks require models to generalize on distributions diffe...

Early Mechanisms of Left-Right Symmetry Breaking in Amniote Gastrulation

Early Origin of Left-Right Asymmetry in Embryonic Development Academic Background Bilateral symmetry is a widely prevalent body structure feature in the animal kingdom. However, while vertebrates exhibit bilateral symmetry externally, their internal organs display left-right (LR) asymmetry. This asymmetry plays a crucial role during embryonic devel...

Contextual Neural Dynamics during Time Perception in the Primate Ventral Premotor Cortex

Neural Dynamics of Time Perception in the Ventral Premotor Cortex Academic Background Time perception is one of the central questions in neuroscience, particularly how the brain encodes time information as cognitive demands change. Time can be categorized as “long” or “short,” or it can be precisely represented as continuous intervals. The ventral ...

Active Vision in Freely Moving Marmosets Using Head-Mounted Eye Tracking

Study of Visual Behavior in Freely Moving Primates: Development and Application of an Innovative Eye-Tracking System Academic Background The visual system is one of the most extensively studied areas within the primate nervous system, particularly concerning the mechanisms of visual pathways in the cerebral cortex. However, current research on how ...

Evidence for Domain-General Arousal from Semantic and Neuroimaging Meta-Analyses Reconciles Opposing Views on Arousal

Neuroscientific Research Report on “Domain-General Arousal” Academic Background Arousal is a core concept in neuroscience, referring to fluctuations in brain and body states that underpin motivated behavior. Despite the widespread use of the term “arousal,” its definition has remained ambiguous, with differing interpretations in various textbooks. ...

Cataract-Prone Variants of γD-Crystallin Populate a Conformation with a Partially Unfolded N-Terminal Domain under Native Conditions

Study on Partially Unfolded Intermediate of γD-Crystallin Variants under Native Conditions Academic Background Human γD-crystallin is a structural protein in the eye lens, crucial for maintaining its transparency and stability. It must remain folded throughout an individual’s lifetime to avoid aggregation and protein deposition, thus preventing cat...

Human MAIT Cell Response Profiles Biased Toward IL-17 or IL-10 Are Distinct Effector States Directed by the Cytokine Milieu

Functional Plasticity of Human MAIT Cells and Their Role in Immune Regulation Academic Background Mucosal-Associated Invariant T cells (MAIT cells) are a type of unconventional T lymphocyte found abundantly in healthy humans, especially in mucosal tissues. MAIT cells exhibit innate-like characteristics, rapidly recognizing antigens derived from mic...

Spatial Patterning Analysis of Cellular Ensembles (SPACE) Detects Complex Spatial Organization at the Cell and Tissue Levels

Spatial Patterning Analysis of Cellular Ensembles (SPACE): Revealing Complex Spatial Patterns in Biological Tissues Academic Background The function of biological tissues depends on the interactions of cells, molecules, and structures in three-dimensional space. Understanding these spatial organization patterns can provide new insights into patholo...