Research Report on the Realization of Blue-Ultraviolet Light Mode-Locking by Polariton Waveguides In the field of modern optoelectronics, continuous advancements in laser technology have greatly propelled the development of information technology, biomedicine, and industrial processing, among other sectors. Mode-locked laser technology, in particul...
Requirement for Orbital Angular Momentum Comb Modes in Digital Lasers Research Background and Significance With the rapid advancement of information technology, the demand for high-capacity data transmission has become increasingly stringent. Orbital angular momentum (OAM) of light, due to its inherently infinite dimensions, is considered a potenti...
Research Report: Electrically Controlled Engineering of Synthetic Magnetic Fields in Polarized Photons Academic Background and Research Purpose In recent years, synthetic gauge theory has shown its potential in controlling the propagation of light and its state evolution in non-magnetic photonic systems. However, the synthetic magnetic fields gener...
Broadband Achromatic Spatial Differential Imaging with Optical Spin-Orbit Coupling Background Introduction In image processing, traditional spatial differentiation is typically accomplished through digital electronic computation. However, many big data applications require real-time and high-throughput image processing, which poses a tremendous cha...
Research Report on Claudin 18.2 in Gastric Cancer and Gastroesophageal Junction Adenocarcinoma Background Introduction Gastric cancer and gastroesophageal junction (G/GEJ) adenocarcinoma are major global health burdens. It is estimated that in 2020 alone, there were approximately 1.7 million new cases of gastric and esophageal cancers worldwide, wi...
Study on Real-world Outcomes of First-line Immune Checkpoint Inhibitor Therapy in Metastatic Melanoma Predicted by Tumor Mutational Burden The treatment of metastatic melanoma has significantly benefited from immune checkpoint inhibitors (ICIs) in recent years. However, despite the remarkable improvement in survival rates among melanoma patients, t...
The Use of Regorafenib in Patients with BRAF-Mutant Solid Tumors: A Summary of Results from the TAPUR Study Background Introduction The BRAF gene belongs to the cytoplasmic serine/threonine kinase family and regulates cell proliferation and survival by activating the mitogen-activated protein kinase signaling pathway (MAPK). BRAF mutations can lead...
In contemporary clinical oncology practice and drug development, the methods for evaluating tumor response are on the cusp of a revolution. Since the World Health Organization (WHO) proposed tumor response classification criteria for assessing the effectiveness of anti-cancer drugs in 1981, this field has undergone several improvements. Notably, th...
Transcriptomic Analysis of Prostate Cancer Patients: A Study on Nonlocalized Disease Based on Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography Academic Background Prostate cancer is a common male malignancy, and its diagnosis and treatment are crucial to patient prognosis. Transcriptomic analysis is a technique us...
Study on the Efficacy of Erdafitinib in Patients with Tumors with FGFR Mutations or Fusions This academic report is based on the scientific paper “Phase II Study of Erdafitinib in Patients with Tumors with Fibroblast Growth Factor Receptor Mutations or Fusions: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol K2,” and introduces the...