Study on the Neuroregulatory Effects of Meditation: A Case Study of Loving-Kindness Meditation Academic Background Meditation, as a mental training technique, has long been believed to regulate emotions and enhance mental health. Specifically, Loving-Kindness Meditation (LKM), which focuses on cultivating positive emotions towards oneself and other...
Multi-Ancestry Genome-Wide Association Study Reveals New Loci for Prostate-Specific Antigen Levels and Improves Prediction Across Ancestral Groups Research Background and Problem Statement Prostate-specific antigen (PSA) is a protein secreted by the prostate gland, commonly used for prostate cancer screening. However, PSA levels are influenced not ...
Research Background and Problem Statement Hereditary Folate Malabsorption (HFM) is a rare autosomal recessive disorder characterized by impaired intestinal absorption of folates and hindered transport across the choroid plexus into cerebrospinal fluid. This disease is caused by inactivating mutations in the gene encoding the Proton-Coupled Folate T...
A New Framework for Multi-Trait Rare Variant Analysis: Multistaar Research Background and Problem Statement With the advancement of next-generation sequencing technologies and the decreasing cost of whole-genome sequencing (WGS), researchers can delve deeper into the impact of rare variants on complex human traits. However, single-trait analysis me...
Research Background and Question In modern society, the patterns of physical activity (PA) and their impact on health have been a critical area of public health and medical research. Traditional studies have primarily focused on the total volume and intensity of physical activity. However, in recent years, an increasing number of studies have begun...
Research Background Current Status and Challenges in Hidradenitis Suppurativa Research Hidradenitis Suppurativa (HS) is a relatively common and highly morbid inflammatory skin disease. It affects approximately 1% of the global population, disproportionately impacting women and marginalized groups. HS’s pathogenesis is complex, involving genetic, im...
Development and Validation of a Time-Varying Correction Factor for QT Interval Assessment in Drug-Resistant Tuberculosis Patients Academic Background and Research Motivation During the treatment of active tuberculosis (Tuberculosis, TB), patients often experience tachycardia (Tachycardia), which typically diminishes as they recover. Elevated heart ...
Same Data, Different Analysts: The Impact of Analytical Decisions on Effect Sizes in Ecology and Evolutionary Biology Research Background and Question In scientific research, particularly in the fields of ecology and evolutionary biology, the replicability and reliability of results are crucial. However, even when using the same dataset and similar...
The Role of Electroencephalography in Epilepsy Research: From Seizures to Interictal Activity and Comorbidities Academic Background Since the early 20th century, electroencephalography (EEG) has been a key tool in epilepsy research. EEG technology not only helps scientists record and analyze brain signals but also reveals the pathophysiological mec...
Neurocritical Care Organization in Low- and Middle-Income Countries Academic Background and Problem Statement Neurocritical care (NCC) has rapidly evolved over the past few decades as a distinct subspecialty of critical care medicine. Evidence shows that patients with acute brain injuries have significantly improved outcomes when treated in dedicat...