Investigating Useful Features for Overall Survival Prediction in Patients with Low-Grade Glioma Using Histology Slides

Useful Features for Overall Survival Prediction in Low-Grade Glioma Patients Academic Background Glioma is a type of neoplastic growth in the brain that usually poses a serious threat to the patients’ lives. In most cases, glioma eventually leads to the death of the patient. The analysis of glioma typically involves examining pathological slices of...

Prediction of Glioma Grade Using Intratumoral and Peritumoral Radiomic Features from Multiparametric MRI Images

“Prediction of Glioma Grades Based on Radiomic Features Inside and Outside Tumors Using Multiparametric MRI Images” Research Background Glioma is the most common primary brain tumor in the central nervous system, accounting for 80% of adult malignant brain tumors. In clinical practice, treatment decisions often require individualized adjustments ba...

First Clinical Investigation of Near-Infrared Window IIA/IIB Fluorescence Imaging for Precise Surgical Resection of Gliomas

First Clinical Investigation of Near-Infrared Window IIA/IIB Fluorescence Imaging for Precise Surgical Resection of Gliomas

“IEEE Transactions on Biomedical Engineering” August 2022, Vol. 69, No. 8, First Clinical Study: Application of Near-Infrared Window IIA/IIB Fluorescence Imaging in Precise Glioma Resection Surgery Cao Caiguang, Jin Zeping, Shi Xiaojing, Zhang Zhe, Xiao Anqi, Yang Junying, Ji Nan, Tian Jie (IEEE Member), Hu Zhenhua (IEEE Senior Member) Introduction...

Bayesian Inference of Tissue Heterogeneity for Individualized Prediction of Glioma Growth

Personalized Prediction of Glioma Growth Using Bayesian Inference Introduction Glioblastoma is the most aggressive type of primary brain tumor, characterized by highly invasive tumor cells that spread to surrounding tissues. Conventional medical imaging techniques cannot precisely identify these diffuse tumor boundaries, leading to suboptimal clini...

A Numerical Analysis of Rectangular Open Channel Embedded TiO2-Au-MXene Employed PCF Biosensor for Brain Tumor Diagnosis

Numerical Analysis of Rectangular Open-Channel PCF Biosensor Embedded with TiO2-Au-MXene for Brain Tumor Diagnosis Academic Background and Problem Statement In recent years, the development of cost-effective and highly reliable biosensors has become a research hotspot. These sensors aim to detect minute concentrations of analytes and cover a wide a...

Modeling of Glioma Growth with Mass Effect by Longitudinal Magnetic Resonance Imaging

Study of Mathematical Models for Tumor Growth – Exploring Glioma Extension Using Longitudinal Magnetic Resonance Imaging A recent article published in the IEEE Transactions on Biomedical Engineering presents a systematic study on the mathematical modeling and growth patterns of gliomas (glioma). This research was conducted by Birkan Tunç, David A. ...

Comparison of Sonication Patterns and Microbubble Administration Strategies for Focused Ultrasound-Mediated Large-Volume Drug Delivery

Comparison of Acoustic Patterns and Microbubble Delivery Strategies in Large-Volume Drug Delivery Mediated by Focused Ultrasound for Blood-Brain Barrier Opening Background Diffuse Intrinsic Pontine Glioma (DIPG) is the most common and lethal brainstem tumor in children. Due to the usually intact blood-brain barrier (BBB) in DIPG, drug penetration i...

St. Jude Survivorship Portal: Sharing and Analyzing Large Clinical and Genomic Datasets from Pediatric Cancer Survivors

St. Jude Survivorship Portal: Sharing and Analyzing Large Clinical and Genomic Datasets from Pediatric Cancer Survivors

St. Jude Survivorship Portal: Analysis and Sharing of Large-Scale Clinical and Genomic Data of Pediatric Cancer Survivors Research Background In the United States, the five-year survival rate for childhood cancer has increased from about 60% in the 1970s to over 85% today. Despite the significant improvement in survival rates, these childhood cance...

Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells

In the current field of tumor treatment, precision medicine continues to be a research hotspot and development trend. With the advancement of science and technology, we have begun to more accurately understand the characteristics of tumor cells and their dependencies for survival, in hopes of finding new therapeutic targets. Particularly, strategie...

Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection

Clinical Validation Study on the Application of Cell-Free DNA Fragment Analysis in Enhancing Early Detection of Lung Cancer Background Lung cancer is one of the leading types of cancer threatening the health of both men and women globally. Over 125,000 people die from lung cancer in the United States each year, and globally, the number is close to ...