Ventilation Practices in Acute Brain Injured Patients and Association with Outcomes: The Ventibrain Multicenter Observational Study

Medicine, Neurology,
mechanical ventilation   acute brain injury   traumatic brain injury   cerebrovascular disease   outcome  

Academic Report on “Ventilation Practices in Acute Brain Injured Patients and Association with Outcomes: The Ventibrain Multicenter Observational Study” Academic Background Mechanical ventilation (MV) is a fundamental component of the intensive care unit (ICU) management of acute brain injury (ABI) patients. However, strong evidence on the best ven...

Discussing Expected Long-Term Quality of Life in the ICU: Effect on Experiences and Outcomes of Patients, Family, and Clinicians—A Randomized Clinical Trial

Medicine, Nursing, Emergency Medicine, Psychiatry, Clinical Psychology,
critical care outcomes   shared decision-making   quality of life   prediction model   ICU   depression symptoms   clinician collaboration  

The Impact of Discussing Long-Term Quality of Life Predictions in the ICU on Patients, Families, and Healthcare Professionals Academic Background Patients discharged from the Intensive Care Unit (ICU) often face a range of physical, psychological, and cognitive issues, collectively referred to as Post-Intensive Care Syndrome (PICS). Despite improve...

Persistent Severe Acute Kidney Injury is a Major Modifiable Determinant of Outcome During Critical Illness

Medicine, Nephrology,
Acute Kidney Injury   Critical Illness   Renal Recovery   Risk Factors   Renal Replacement Therapy  

The Impact of Persistent Severe Acute Kidney Injury on Outcomes in Critically Ill Patients Background Introduction Acute Kidney Injury (AKI) is a common complication among hospitalized and critically ill patients, causing over 10 million deaths globally each year and serving as a significant risk factor for the progression of Chronic Kidney Disease...

ESICM Consensus-Based Recommendations for the Management of Very Old Patients in Intensive Care

Medicine, Emergency Medicine, Geriatrics, Anesthesiology,
critical care   delphi study   emergency medicine   geriatric medicine   very old patients  

ESICM Consensus: Management and Challenges of Very Old Patients in Critical Care Academic Background With the global aging population, the proportion of “very old patients” (aged 80 years and above) in intensive care units (ICUs) is rapidly increasing. This group is characterized by functional impairments and a high prevalence of complex multimorbi...

Are Contemporary Antifungal Doses Sufficient for Critically Ill Patients? Outcomes from an International, Multicenter Pharmacokinetics Study for Screening Antifungal Exposure in Intensive Care Units—The SAFE-ICU Study

Medicine, Infectious Diseases, Pharmacy,
antifungals   pharmacokinetics   intensive care unit   invasive fungal disease   dose optimization  

International Multicenter Study Reveals Insufficient Antifungal Dosing in Critically Ill Patients Academic Background Invasive fungal infections are common and serious nosocomial infections, particularly among patients in the intensive care unit (ICU), where they are associated with high morbidity and mortality rates. Timely and appropriate antifun...

Impact of Rapid ICU-Based Syndromic PCR on Antibiotic Stewardship and Clinical Outcomes in Hospital-Acquired and Ventilator-Associated Pneumonia

Medicine, Infectious Diseases, Medical Laboratory Science,
Hospital-acquired pneumonia   Ventilator-associated pneumonia   Multiplex PCR   Antibiotic stewardship   Clinical outcomes  

INHALE WP3 Study - The Impact of Rapid PCR on ICU Antibiotic Stewardship and Clinical Outcomes Background Introduction Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are common infections in intensive care unit (ICU) patients, with an incidence rate between 5% to 40%, and are associated with high morbidity and increased...

Effectiveness of Bundle of Care on Tolerance of Awake-Prone Positioning in Patients with Acute Respiratory Failure: A Multicenter Observational Study

Medicine, Nursing, Respiratory System,
acute respiratory failure   awake-prone positioning   multicenter study   bundle of care   high-flow nasal oxygen  

Effectiveness Study of Awake Prone Positioning Care Strategies in Patients with COVID-19 Related Acute Respiratory Failure Background Introduction During the COVID-19 pandemic, acute respiratory failure (Acute Respiratory Failure, ARF) became one of the main complications in critically ill patients. For patients requiring high-flow nasal oxygen (Hi...

Role of Major Cardiovascular Surgery-Induced Metabolic Reprogramming in Acute Kidney Injury in Critical Care

Medicine, Nephrology, Cardiovascular System, Life Sciences, Biochemistry,
major cardiovascular surgery   metabolism   metabolomics   amino acid   TCA cycle   citric acid   acylcarnitines   acute kidney injury  

The Role of Major Cardiovascular Surgery-Induced Metabolic Reprogramming in Acute Kidney Injury: A Metabolomics Study Academic Background Cardiovascular diseases are the leading cause of death worldwide, accounting for over 17.9 million deaths annually, which is 32% of all deaths. As the disease burden increases, about one-third of patients may req...

A Multivariable Prediction Model for Invasive Pulmonary Aspergillosis in Immunocompromised Patients with Acute Respiratory Failure (IPA-GRRR-OH Score)

Medicine, Infectious Diseases, Oncology, Life Sciences, Immunology,
Invasive Pulmonary Aspergillosis   Immunocompromised   Acute Respiratory Failure   Prediction Model   Intensive Care  

A Prediction Model for Invasive Pulmonary Aspergillosis in Immunocompromised Patients with Acute Respiratory Failure Background Introduction Invasive Pulmonary Aspergillosis (IPA) is a severe opportunistic infection commonly seen in immunocompromised patients, particularly those with immune dysfunction caused by hematological malignancies, stem cel...

Serum Chloride Concentration and Outcomes in Adults Receiving Intravenous Fluid Therapy

Medicine, Emergency Medicine, Nephrology,
intravenous fluid therapy   saline   balanced multi-electrolyte solutions   intensive care   resuscitation   chloride   acidosis  

The Relationship Between Serum Chloride Concentration and Intravenous Fluid Therapy Outcomes Background Introduction In the intensive care unit (ICU), intravenous fluid therapy is a common treatment, with “balanced solutions” and 0.9% sodium chloride solution (saline) being the most commonly used fluids. In recent years, multiple randomized control...