Inflammatory Bowel Disease (IBD) is a chronic inflammatory condition that primarily includes Ulcerative Colitis (UC) and Crohn’s Disease (CD). The incidence of IBD has been increasing globally, imposing significant health and economic burdens on patients and society. Currently, the diagnosis of IBD relies mainly on endoscopy, but this method is exp...

In recent years, the significant role of the human gut microbiota (HGM) in the metabolism of drugs and nutrients has gradually been recognized. The gut microbiota not only affects the bioavailability of orally administered drugs but also participates in the biotransformation of drugs and bioactive molecules through its metabolic enzymes, thereby in...

Flatulence is a common occurrence in daily life, often resulting from the fermentation of undigested food components by the gut microbiota. While flatulence is generally harmless, it can lead to discomfort, bloating, and even chronic conditions such as irritable bowel syndrome (IBS). Certain foods, particularly those rich in dietary fiber like bean...

In recent years, the role of gut microbiota in health and disease has garnered widespread attention. Research indicates that the diversity and composition of gut microbiota are closely related to the development and progression of cardiovascular disease (CVD). CVD is one of the leading causes of death globally, and inflammation plays a significant ...

The Key Role of Human Milk Microbes and Oligosaccharides in Infant Gut Microbiota Development Academic Background The development of infant gut microbiota is crucial in early life, and breastfeeding is one of the key drivers of this process. Human milk not only provides essential nutrients for infants but also contains a rich array of microbes and ...

In recent years, the role of the gut microbiome in human health and disease has garnered significant attention. Research indicates that gut microbial dysbiosis is closely associated with various chronic diseases, such as obesity, inflammatory bowel disease, cancer, and neurodegenerative disorders. Diet, as a critical factor influencing the gut micr...

Academic Background Pregnant women undergo significant physiological changes in their cardiovascular system to meet the increased physiological demands during pregnancy. Among these changes, an increase in resting heart rate (HR) is common, typically rising by 10-20 beats per minute. However, this increase in HR can lead to the onset or exacerbatio...

Background Introduction Atherosclerosis is a complex vascular disease characterized by the progressive accumulation of lipid plaques within the arterial walls, ultimately leading to cardiovascular events such as myocardial infarction, stroke, and peripheral vascular disease. Although the current standard treatment regimen includes statins and antip...

Academic Background Interleukin 11 (IL-11) is a member of the IL-6 cytokine family and was initially thought to play an important role in platelet production, leading to its development as a drug for treating thrombocytopenia. However, subsequent research found that IL-11 is not essential for hematopoiesis, and its use in patients is associated wit...

Heart Failure (HF) is a complex disease with increasing incidence and poor prognosis. Cardiac cachexia, a common complication in HF patients, is characterized by significant weight loss, muscle wasting, and malnutrition, and its occurrence is independently associated with patient morbidity and mortality. Although cardiac cachexia is prevalent in HF...