Academic Background Caregivers of patients with Primary Malignant Brain Tumors (PMBT) face significant psychological distress. PMBT is not only an incurable cancer but also accompanied by degenerative neurological conditions, leading caregivers to cope with the gradual loss of the patient’s physical functions and irreversible changes in personality...

Academic Background and Problem Statement Epithelial Ovarian Cancer (EOC) remains one of the leading causes of death among gynecologic malignancies. Although the incorporation of molecularly targeted therapies, such as bevacizumab and PARP inhibitors, has improved Progression-Free Survival (PFS) and, in some cases, Overall Survival (OS), many patie...

Academic Background and Problem Acute lymphoblastic leukemia (ALL) is a malignant hematologic disease, particularly challenging to treat in older patients, with limited treatment options and poor outcomes. Traditional chemotherapy regimens yield long-term survival rates of only 20%-30% in elderly patients. Therefore, finding more effective and bett...

Impact of Adjuvant Chemotherapy on Resected Intraductal Papillary Mucinous Neoplasm-Derived Pancreatic Cancer: Results from an International Multicenter Study Academic Background Intraductal Papillary Mucinous Neoplasm (IPMN) is the most common type of pancreatic cyst, and its incidence and prevalence have been increasing due to the widespread use ...

Delivering High-Quality Cancer Care: A Decade Later Academic Background In 2012, the National Academies of Sciences, Engineering, and Medicine (NASEM) convened a committee to address the quality of cancer care in the United States and provide recommendations to policymakers and the cancer care community on strategies to improve cancer care delivery...

Academic Background Breast cancer is one of the most common cancers among women worldwide, particularly triple-negative breast cancer (TNBC) and hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) breast cancer, which are known for their aggressive nature and poor prognosis. In recent years, immune checkpoint inh...

Academic Background Ovarian cancer is one of the most common malignancies of the female reproductive system. Despite recent advancements in treatment, the recurrence rate remains high, particularly in patients with late relapse. Platinum-based chemotherapy (CT) is the standard treatment for ovarian cancer, and poly (ADP-ribose) polymerase (PARP) in...

Diagnostic Accuracy of Dynamic CT Perfusion in Patients with Coronary Stents Academic Background Coronary artery disease (CAD) is one of the leading causes of death worldwide. Percutaneous coronary intervention (PCI) is a common treatment for obstructive CAD. However, after stent implantation, patients may experience in-stent restenosis (ISR) or pr...

Prognostic Value of Coronary CT Angiography-Derived Quantitative Flow Ratio in Suspected Coronary Artery Disease Academic Background Coronary artery disease (CAD) is one of the leading causes of death and disability worldwide. Coronary CT angiography (CTA) is recommended as a first-line noninvasive test for patients with suspected or known CAD. CTA...

Report on the Increasing Rates of Distant-Stage Breast Cancer in U.S. Women Academic Background Breast cancer is the second leading cause of cancer death among U.S. women, following lung cancer. Although screening mammography has been shown to significantly reduce breast cancer mortality, screening rates in the U.S. remain low, particularly among w...