Lateralization of Dorsal Fiber Tract Targeting Broca’s Area Concurs with Language Skills During Development

Lateralization of Dorsal Fiber Tract Targeting Broca’s Area Concurs with Language Skills During Development

New Discoveries in Brain Science: The Relationship Between Early Lateralization of Dorsal White Matter Tracts Targeting Broca’s Area and Language Development Research Background Language development is one of the key areas in human cognitive science. Existing research indicates that language functions in the adult brain exhibit significant laterali...

Decoding the Influence of Central LEAP2 on Food Intake and Its Effect on Accumbal Dopamine Release

Analysis of the Effect of Central LEAP-2 on Food Intake and Its Impact on Nucleus Accumbens Dopamine Release Background Introduction Gut-brain peptides such as ghrelin and their receptors have been established as important factors in regulating hunger and reward processing. However, the liver-expressed antimicrobial peptide 2 (Leap2), an inverse ag...

Control of goal-directed and inflexible actions by dorsal striatal melanocortin systems, in coordination with the central nucleus of the amygdala

This academic paper, authored by researchers Elizabeth C. Heaton, Esther H. Seo, Laura M. Butkovich, Sophie T. Yount, and Shannon L. Gourley, primarily explores the role of the melanocortin system in the dorsal striatum in controlling goal-directed behavior and inflexible behavior, particularly in inhibiting habitual behavior in the dorsolateral st...

Prefrontal-Subthalamic Theta Signaling Mediates Delayed Responses During Conflict Processing

Prefrontal-Subthalamic Theta Signaling Mediates Delayed Responses During Conflict Processing

The Role of Prefrontal-Subthalamic θ Signals in Regulating Delayed Responses in Conflict Processing Background and Research Objectives Conflict processing plays a crucial role in human behavioral regulation. When faced with conflicting information, making an accurate decision requires delaying the response to gain time to choose the appropriate beh...

Genome-Wide Repeat Landscapes in Cancer and Cell-Free DNA

Genome-Wide Repeat Landscapes in Cancer and Cell-Free DNA

A Panoramic View of Whole Genome Repetitive Sequences in Cancer and Circulating Free DNA Research Background and Significance Throughout the development of cancer and other diseases, genetic changes in repetitive sequences within the genome are a significant characteristic. However, standard sequencing methods struggle to effectively characterize t...

An Electroencephalogram Microdisplay to Visualize Neuronal Activity on the Brain Surface

An Electroencephalogram Microdisplay to Visualize Neuronal Activity on the Brain Surface

A Visualization Microdisplay for Neuronal Activity on the Brain Surface Using Electroencephalography Background Introduction Current functional mapping in neurosurgery primarily relies on verbal communication between neurosurgeons and electrophysiologists. These processes are time-consuming and have limited resolution. Additionally, the electrode g...

Multimodal MRI Reveals Brainstem Connections That Sustain Wakefulness in Human Consciousness

Multimodal MRI Reveals Brainstem Connections That Sustain Wakefulness in Human Consciousness

Major Breakthrough in Brain Science: Multimodal MRI Reveals Brainstem Connectivity Maintaining Human Consciousness and Wakefulness Background Introduction Consciousness comprises two fundamental components: wakefulness and awareness. Despite significant progress in understanding the cortical networks related to consciousness over the past two decad...

Electronic Health Record Signatures Identify Undiagnosed Patients with Common Variable Immunodeficiency Disease

Electronic Health Record Signatures Identify Undiagnosed Patients with Common Variable Immunodeficiency Disease

Utilizing Electronic Health Record Features to Identify Undiagnosed Patients with Common Subtype of Immunodeficiency Recently, Johnson and colleagues published a study titled “Electronic health record signatures identify undiagnosed patients with common variable immunodeficiency disease” in Science Translational Medicine. This research utilizes ele...

Nociceptor Spontaneous Activity is Responsible for Fragmenting Non-Rapid Eye Movement Sleep in Mouse Models of Neuropathic Pain

Research Background and Motivation Neuropathic pain is a complex and common clinical issue, accompanied by persistent spontaneous pain. Patients often report symptoms such as spontaneous pain, electric shock sensations, and burning pain. The physiological mechanisms behind this type of pain are complex, and reliable research models or biomarkers ar...

Volumetric Microscopy of Cerebral Arteries with a Miniaturized Optical Coherence Tomography Imaging Probe

Volumetric Microscopy of Cerebral Arteries with a Miniaturized Optical Coherence Tomography Imaging Probe

New Breakthrough in the Field of Cerebral Vascular Diseases: Clinical Application of Small Optical Coherence Tomography Imaging Probe Academic Background and Research Motivation In recent years, interventional treatment has become the preferred method for cerebrovascular diseases such as cerebral aneurysm, ischemic stroke, arterial dissection, and ...