Sexual Dimorphism in the Mouse Kidney-Brain Connectome In recent years, an increasing number of studies have shown that kidney function is not only influenced by local self-regulation and hormonal systems but is also largely regulated by the nervous system. Although it is known that there are multi-synaptic anatomical connections between central au...

Behavioral Characterization of Shank3B Mice Across Both Sexes Research Background Autism Spectrum Disorder (ASD) is a group of complex mental disorders characterized by abnormalities in social interaction and repetitive behaviors. The Shank3B mutant ASD mouse model is widely used in research; however, the behavioral phenotype of this model has not ...

Neural computational mechanisms underlying fairness-based decisions: Self-Unfairness and Other-Unfairness Abstract: Fairness is a fundamental value in human society, and individuals show concern for both self-unfairness and other-unfairness. However, there has been a long-standing debate on whether self-unfairness and other-unfairness evoke shared ...

Neural Mechanism | Neural Basis of Animal Body Silhouette Classification This article, written by Yue Pu and Shihui Han, published in “neurosci. bull.” in 2024, explores the neural processes of rapid classification and cognition of animal body silhouettes in humans. The study aims to reveal how humans identify and categorize individuals of differen...

Differences in Brain Cortical Morphological Networks Between Gyri and Sulci Introduction The human brain, as an interconnected complex network, can be mapped through virtual imaging using multimodal magnetic resonance imaging (MRI) technology. By analyzing this network using graph theory methods, many studies have discovered some non-trivial topolo...

Fluoxetine Rescues Excessive Myelin Formation and Psychological Behaviors in a Murine PTSD Model Background Post-traumatic stress disorder (PTSD) is a complex mental disorder characterized by spontaneous intrusions of traumatic memories, avoidance of trauma-related stimuli, negative emotions and cognitions, and hyperarousal. Although existing first...

Study on Serum LDL Promoting Microglial Activation and Exacerbating Demyelination in Neuromyelitis Optica Spectrum Disorder Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune inflammatory demyelinating disease of the central nervous system (CNS), often accompanied by disruption of the blood-brain barrier (BBB). Dysfunction of lipid met...

Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Project to Bed Nucleus of the Stria Terminalis to Regulate Wakefulness and Positive Emotional States Background The nucleus accumbens (NAc) plays a crucial role in regulating motivation, reward, and many behaviors that depend on high levels of arousal. However, research on the neural mechani...

In the field of neuroscience, epilepsy has always been a disease of great concern, with significant challenges remaining in clinical research and treatment. Among these, the issue of secondary epileptogenesis has had a profound impact on academia and clinical treatment. Secondary epileptogenesis refers to the continuous spread of epileptic activity...

The Role of Occipitotemporal Network in Rapid Reading - An fMRI-based Study Background Reading is the most effective cognitive means for humans to acquire new knowledge. Although most native English-speaking adults read at an average speed of about 200 to 400 words per minute (w/min), many people hope to increase their reading speed to acquire new ...